Journal article
Deciphering Stem Cell From Apical Papilla–Macrophage Choreography Using a Novel 3-dimensional Organoid System
Abstract
INTRODUCTION: Immune cell-mesenchymal stem cell crosstalk modulates the process of repair and regeneration. In this study, a novel heterogeneous cell containing a matrix-based 3-dimensional (3D) tissue construct was used to study the interactions between stem cells from apical papilla (SCAPs) and macrophage for a comprehensive understanding on the cellular signaling mechanisms guiding inflammation and repair.
METHODS: SCAPs and macrophages were …
Authors
Li F-C; Hussein H; Magalhaes M; Selvaganapathy PR; Kishen A
Journal
Journal of Endodontics, Vol. 48, No. 8, pp. 1063–1072.e7
Publisher
Elsevier
Publication Date
August 2022
DOI
10.1016/j.joen.2022.04.011
ISSN
0099-2399