Comparison of the performance of anion exchange membrane materials for adenovirus purification using laterally-fed membrane chromatography

Viruses are an emerging class of biotherapeutics used to treat a variety of diseases. Ion-exchange membrane chromatography is commonly used for virus purification, with the Mustang Q (Pall) and Sartobind Q (Sartorius) being two of the most widely used strong anion-exchange membranes. These membranes are made from different materials and have different pore sizes, and while previous studies have attempted to compare their performance in various …