Duration of use and outcomes among people with opioid use disorder initiating methadone and buprenorphine in Ontario: a population‐based propensity‐score matched cohort study

Abstract

AIMS: To characterize comparative risks and benefits of methadone versus buprenorphine/naloxone in a contemporary cohort where the unregulated drug supply is dominated by fentanyl. DESIGN, SETTING AND PARTICIPANTS: Population-based propensity-score matched cohort study conducted in Ontario, Canada among people aged 18+ initiating opioid agonist therapy (OAT) for an opioid use disorder between October 2016 and December 2018 (n = 18 880).

Authors

Gomes T; McCormack D; Bozinoff N; Tadrous M; Antoniou T; Munro C; Campbell T; Paterson JM; Mamdani M; Sproule B

Journal

Addiction, Vol. 117, No. 7, pp. 1972–1981

Publisher

Wiley

Publication Date

July 2022

DOI

10.1111/add.15862

ISSN

0965-2140

Associated Experts

J Michael Paterson

Assistant Professor (Part-Time), Faculty of Health Sciences

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