Journal article
TMOD-23. DEVELOPMENT AND APPLICATION OF A NOVEL MODEL OF HUMAN LUNG-TO- BRAIN METASTASIS TO IDENTIFY GENETIC REGULATORS OF BRAIN METASTASIS INITIATING CELLS
Abstract
Brain Metastases (BM) are the most common type of cerebral tumor in adult, occurring at a rate 10 times greater than that of primary brain cancers. The inherent abilities of a primary tumor cell capable of initiating a BM resembles that of a cancer stem cell (CSCs). We hypothesize that a subgroup of CSCs, termed brain metastasis-initiating cells (BMICs), are responsible for the initiation of BM and are identifiable by an exclusive subset of …
Authors
Singh M; Venugopal C; Tokar T; Brown K; McFarlane N; Bakhshinyan D; Vora P; Qazi M; Mahendram S; Vijaykumar T
Journal
Neuro-Oncology, Vol. 18, No. suppl_6, pp. vi211–vi212
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 2016
DOI
10.1093/neuonc/now212.893
ISSN
1522-8517