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Metabolite profiles and the risk of metabolic...
Journal article

Metabolite profiles and the risk of metabolic syndrome in early childhood: a case-control study

Abstract

BackgroundDefining the metabolic syndrome (MetS) in children remains challenging. Furthermore, a dichotomous MetS diagnosis can limit the power to study associations. We sought to characterize the serum metabolite signature of the MetS in early childhood using high-throughput metabolomic technologies that allow comprehensive profiling of metabolic status from a biospecimen.MethodsIn the Family Atherosclerosis Monitoring In earLY life (FAMILY) …

Authors

Azab SM; de Souza RJ; Lamri A; Shanmuganathan M; Kroezen Z; Schulze KM; Desai D; Williams NC; Morrison KM; Atkinson SA

Journal

BMC Medicine, Vol. 19, No. 1,

Publisher

Springer Nature

Publication Date

December 2021

DOI

10.1186/s12916-021-02162-7

ISSN

1741-7015