DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation

BackgroundDrug repositioning, the strategy of unveiling novel targets of existing drugs could reduce costs and accelerate the pace of drug development. To elucidate the novel molecular mechanism of known drugs, considering the long time and high cost of experimental determination, the efficient and feasible computational methods to predict the potential associations between drugs and targets are of great aid.MethodsA novel calculation model for …