Journal article
Effect of 5-hydroxytryptamine (serotonin) receptor inhibitors on the radiation-induced bystander effect
Abstract
PURPOSE: To test the importance of serotonin as a signaling molecule involved in the production and response of radiation-induced bystander effects.
MATERIALS AND METHODS: HPV-G human keratinocyte cultures were spiked with various concentrations of Granisetron or Ketanserin and subject to either 0 Gy or 0.5 Gy X-irradiation to observe the inhibitor's effects on bystander signal production. Medium from these cultures was harvested and introduced …
Authors
Fazzari J; Mersov A; Smith R; Seymour C; Mothersill C
Journal
International Journal of Radiation Biology, Vol. 88, No. 10, pp. 786–790
Publisher
Taylor & Francis
Publication Date
October 2012
DOI
10.3109/09553002.2012.714519
ISSN
0955-3002