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Bystander effects in tumor-free and tumor-bearing...
Journal article

Bystander effects in tumor-free and tumor-bearing rat brains following irradiation by synchrotron X-rays

Abstract

PURPOSE: Synchrotron microbeam radiation therapy (MRT) is a radiosurgery concept in the preclinical stage, developed mainly for brain tumor treatment. Experimental studies suggest that with MRT a better therapeutic index can be obtained than with homogenous field radiotherapy, but the underlying cellular mechanisms need further understanding. The aim of this study was to investigate the dynamics of radiation-induced bystander effects (RIBE) in …

Authors

Fernandez-Palomo C; Schültke E; Smith R; Bräuer-Krisch E; Laissue J; Schroll C; Fazzari J; Seymour C; Mothersill C

Journal

International Journal of Radiation Biology, Vol. 89, No. 6, pp. 445–453

Publisher

Taylor & Francis

Publication Date

June 2013

DOI

10.3109/09553002.2013.766770

ISSN

0955-3002