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A Validated Risk Prediction Model for Bone...
Journal article

A Validated Risk Prediction Model for Bone Fragility in Children With Acute Lymphoblastic Leukemia

Abstract

Although bone fragility may already be present at diagnosis of pediatric acute lymphoblastic leukemia (ALL), routine performance of dual-energy X-ray absorptiometry (DXA) in every child is not universally feasible. The aim of this study was to develop and validate a risk prediction model for low lumbar spine bone mineral density (LS BMD Z-score ≤ -2.0) at diagnosis, as an important indicator for fracture risk and further treatment-related BMD …

Authors

Verwaaijen EJ; Ma J; de Groot‐Kruseman HA; Pieters R; van der Sluis IM; van Atteveld JE; Halton J; Fernandez CV; Hartman A; de Jonge R

Journal

Journal of Bone and Mineral Research, Vol. 36, No. 12, pp. 2290–2299

Publisher

Oxford University Press (OUP)

Publication Date

December 1, 2020

DOI

10.1002/jbmr.4442

ISSN

0884-0431