Journal article
THE EFFECT OF COMBINING ALLELES INTO ELECTROPHORETIC CLASSES ON DETECTING LINKAGE DISEQUILIBRIUM
Abstract
When alleles are combined into few detectable classes, linkage correlations are underestimated most of the time. The probability that the linkage correlation will be underestimated is a function of the actual degree of correlation and the evenness of the allelic distribution, but is mainly determined by the distribution of alleles into distinguishable classes. With only two alleles per class this probability will usually be higher than 0.7. …
Authors
Zouros E; Golding GB; MacKay TFC
Journal
Genetics, Vol. 85, No. 3, pp. 543–556
Publisher
Oxford University Press (OUP)
Publication Date
March 1, 1977
DOI
10.1093/genetics/85.3.543
ISSN
0016-6731