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Frequency and Prognostic Significance of Recurrent...
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Frequency and Prognostic Significance of Recurrent Gene Mutations in Pediatric B-ALL: Report from the DFCI ALL Consortium

Abstract

The application of next-generation sequencing (NGS) approaches to leukemia markedly expanded our understanding of the molecular landscape of pediatric acute lymphoblastic leukemia (ALL), but NGS integration into clinical care and therapeutic decision making is still limited. The prognostic impact of discovered mutations in uniformly treated patients with newly diagnosed B-ALL is not well characterized, and there is no consensus regarding the …

Authors

Gotti G; Puligandla M; Stevenson KE; Mar BG; Asselin BL; Athale U; Clavell LA; Cole PD; Gennarini LM; Kahn JM

Volume

136

Pagination

pp. 15-16

Publisher

American Society of Hematology

Publication Date

November 5, 2020

DOI

10.1182/blood-2020-136190

Conference proceedings

Blood

Issue

Supplement 1

ISSN

0006-4971