Journal article
Age of Transfused Blood in Critically Ill Adults
Abstract
BACKGROUND: Fresh red cells may improve outcomes in critically ill patients by enhancing oxygen delivery while minimizing the risks of toxic effects from cellular changes and the accumulation of bioactive materials in blood components during prolonged storage.
METHODS: In this multicenter, randomized, blinded trial, we assigned critically ill adults to receive either red cells that had been stored for less than 8 days or standard-issue red …
Authors
Lacroix J; Hébert PC; Fergusson DA; Tinmouth A; Cook DJ; Marshall JC; Clayton L; McIntyre L; Callum J; Turgeon AF
Journal
The New England Journal of Medicine, Vol. 372, No. 15, pp. 1410–1418
Publisher
Massachusetts Medical Society
Publication Date
April 9, 2015
DOI
10.1056/nejmoa1500704
ISSN
0028-4793