Journal article
Defining the critical hurdles in cancer immunotherapy
Abstract
Scientific discoveries that provide strong evidence of antitumor effects in preclinical models often encounter significant delays before being tested in patients with cancer. While some of these delays have a scientific basis, others do not. We need to do better. Innovative strategies need to move into early stage clinical trials as quickly as it is safe, and if successful, these therapies should efficiently obtain regulatory approval and …
Authors
Fox BA; Schendel DJ; Butterfield LH; Aamdal S; Allison JP; Ascierto PA; Atkins MB; Bartunkova J; Bergmann L; Berinstein N
Journal
Journal of Translational Medicine, Vol. 9, No. 1,
Publisher
Springer Nature
Publication Date
December 2011
DOI
10.1186/1479-5876-9-214
ISSN
1479-5876