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Serum soluble interleukin-2 receptor: A useful...
Journal article

Serum soluble interleukin-2 receptor: A useful indicator of the clinical course in pulmonary tuberculosis

Abstract

SETTING: In tuberculosis both host protection and most pathogenic mechanisms depend on T lymphocytes. After activation by mycobacterial antigens, T cells both secrete interleukin-2 (IL-2) and express a high affinity receptor for this molecule (IL-2R) on their own surface. A soluble fraction of IL-2 receptor (sIL-2R), released from cell membrane, is detectable in serum and its concentration is known to be elevated in tuberculosis. OBJECTIVE: To …

Authors

Inglés MJA; Contessotto C; Rodriguez JO; Alonso AG; Amador MM; Jordana MC; Gascón FS; López RA

Journal

Tuberculosis, Vol. 76, No. 2, pp. 130–135

Publisher

Elsevier

Publication Date

April 1995

DOI

10.1016/0962-8479(95)90555-3

ISSN

1472-9792