selected scholarly activity
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academic article
- Interrupting reactivation of immunologic memory diverts the allergic response and prevents anaphylaxis. Journal of Allergy and Clinical Immunology. 147:1381-1392. 2021
- First contact: Serum amyloid A and pattern recognition in Th2 immunity. Allergy: European Journal of Allergy and Clinical Immunology. 2021
- Peanut allergen reaction thresholds during controlled food challenges in 2 Canadian randomized studies (Canada-ARM1 and PISCES). Journal of Allergy and Clinical Immunology: In Practice. 2021
- Follicular T cells: From stability to failure. Allergy: European Journal of Allergy and Clinical Immunology. 75:1006-1007. 2020
- Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity. Frontiers in Immunology. 11:155. 2020
- Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy. Frontiers in Immunology. 11:603272. 2020
- Human BCR analysis of single-sorted, putative IgE+ memory B cells in food allergy. Journal of Allergy and Clinical Immunology. 144:336-339.e6. 2019
- Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety. The Lancet. 393:2222-2232. 2019
- Microbial regulation of enteric eosinophils and its impact on tissue remodeling and Th2 immunity 2019
- IgG1 + B‐cell immunity predates IgE responses in epicutaneous sensitization to foods. Allergy: European Journal of Allergy and Clinical Immunology. 74:165-175. 2019
- Kaiso-induced intestinal inflammation is preceded by diminished E-cadherin expression and intestinal integrity. PLoS ONE. 14:e0217220-e0217220. 2019
- The IgE memory reservoir in food allergy. Journal of Allergy and Clinical Immunology. 142:1441-1443. 2018
- The Initiation of Th2 Immunity Towards Food Allergens. International Journal of Molecular Sciences. 19:1447-1447. 2018
- Lifelong memory responses perpetuate humoral T H 2 immunity and anaphylaxis in food allergy. Journal of Allergy and Clinical Immunology. 140:1604-1615.e5. 2017
- Prediction of clinical peanut allergy status among children in Hamilton, Ontario using chart review data collected during 2012–2015. Canadian Journal of Allergy and Clinical Immunology Allergy, Asthma and Clinical Immunology. 13:10. 2017
- Probiotics and oral immunotherapy for peanut allergy. The Lancet Child and Adolescent Health. 1:e1-e1. 2017
- CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine–Induced T Cells to Both the Lung Parenchyma and Airway. Journal of Immunology. 199:2555-2569. 2017
- Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection. Journal of Experimental Medicine. 214:1153-1167. 2017
- Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway. PLoS Pathogens. 12:e1005706-e1005706. 2016
- Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway. PLoS Pathogens. 12:e1005589-e1005589. 2016
- TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity. PLoS Pathogens. 12:e1005368-e1005368. 2016
- Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma. Canadian Journal of Allergy and Clinical Immunology Allergy, Asthma and Clinical Immunology. 11:14. 2015
- Intestinal Microbiota Modulates Gluten-Induced Immunopathology in Humanized Mice. American Journal of Pathology. 185:2969-2982. 2015
- Ecobiotherapy Rich in Firmicutes Decreases Susceptibility to Colitis in a Humanized Gnotobiotic Mouse Model. Inflammatory Bowel Diseases. 21:1883-1893. 2015
- Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy. Allergy: European Journal of Allergy and Clinical Immunology. 70:495-505. 2015
- T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunology. 7:1395-1404. 2014
- Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo. Journal of Experimental Medicine. 211:1657-1672. 2014
- Comprehensive metabolomic analysis of peanut-induced anaphylaxis in a murine model. Metabolomics. 10:452-460. 2014
- Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells. Mucosal Immunology. 7:670-683. 2014
- A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure. PLoS ONE. 9:e88714-e88714. 2014
- Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity. PLoS ONE. 9:e114799-e114799. 2014
- IL-13-mediated immunological control of enterochromaffin cell hyperplasia and serotonin production in the gut. Mucosal Immunology. 6:146-155. 2013
- IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization. Journal of Allergy and Clinical Immunology. 131:187-200.e8. 2013
- Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice. Journal of Infectious Diseases. 206:167-177. 2012
- Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection: Genomic Insights. Journal of Immunology. 188:832-843. 2012
- Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation. Respiratory Research. 12:39. 2011
- Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood. Mucosal Immunology. 4:682-694. 2011
- Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma. American Journal of Respiratory Cell and Molecular Biology. 45:753-760. 2011
- Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice. Journal of Allergy and Clinical Immunology. 127:1552-1561.e1. 2011
- A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent. Journal of Immunology. 186:1107-1118. 2011
- Eosinophils Are Dispensable for Allergic Remodeling and Immunity in a Model of House Dust Mite–induced Airway Disease. American Journal of Respiratory and Critical Care Medicine. 183:179-188. 2011
- Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung. Journal of Immunology. 184:2048-2056. 2010
- Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. Journal of Allergy and Clinical Immunology. 124:307-314.e2. 2009
- Spontaneous and induced variability of allergens in commodity crops: Ara h 2 in peanut as a case study. Regulatory Toxicology and Pharmacology. 54:S37-S40. 2009
- Evaluation of allergic lung inflammation by computed tomography in a rat model in vivo. European Respiratory Journal European Respiratory Journal, Supplement. 33:1437-1447. 2009
- Management of Food-Induced Anaphylaxis: Unsolved Challenges. Current Clinical Pharmacology. 4:113-125. 2009
- Acute, but Not Resolved, Influenza A Infection Enhances Susceptibility to House Dust Mite-Induced Allergic Disease. Journal of Immunology. 182:3095-3104. 2009
- TGF-β, Eosinophils and IL-13 in Allergic Airway Remodeling: A Critical Appraisal with Therapeutic Considerations. Current Drug Targets: Inflammation and Allergy Inflammation and Allergy - Drug Targets. 7:224-236. 2008
- Combined budesonide/formoterol therapy in conjunction with allergen avoidance ameliorates house dust mite-induced airway remodeling and dysfunction. American Journal of Physiology - Lung Cellular and Molecular Physiology. 295:L780-L788. 2008
- Induction of Vascular Remodeling in the Lung by Chronic House Dust Mite Exposure. American Journal of Respiratory Cell and Molecular Biology. 39:61-67. 2008
- In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions. PLoS ONE. 3:e2426-e2426. 2008
- Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling. American Journal of Respiratory and Critical Care Medicine. 177:593-603. 2008
- Impact of CD40 Ligand, B Cells, and Mast Cells in Peanut-Induced Anaphylactic Responses. Journal of Immunology. 179:6696-6703. 2007
- Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. American Journal of Physiology - Lung Cellular and Molecular Physiology. 293:L730-L739. 2007
- Th2 Differentiation in Distinct Lymph Nodes Influences the Site of Mucosal Th2 Immune-Inflammatory Responses. Journal of Immunology. 179:3287-3296. 2007
- Immunoreactivity profile of peripheral blood mononuclear cells from patients with ragweed-induced allergic rhinitis. Clinical and Experimental Allergy. 37:901-908. 2007
- Modeling Responses to Respiratory House Dust Mite Exposure. Contributions to microbiology. 14:42-67. 2007
- Generation and Characterization of B7-H4/B7S1/B7x-Deficient Mice. Molecular and Cellular Biology. 26:6403-6411. 2006
- Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues. Journal of Immunology. 176:2568-2580. 2006
- Mainstream Cigarette Smoke Exposure Attenuates Airway Immune Inflammatory Responses to Surrogate and Common Environmental Allergens in Mice, Despite Evidence of Increased Systemic Sensitization. Journal of Immunology. 175:2834-2842. 2005
- House Dust Mite Facilitates Ovalbumin-specific Allergic Sensitization and Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 172:314-321. 2005
- B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance. Journal of Immunology. 174:3000-3005. 2005
- Cutaneous Antigen Priming via Gene Gun Leads to Skin-Selective Th2 Immune-Inflammatory Responses. Journal of Immunology. 174:1664-1674. 2005
- Intranasal Exposure of Mice to House Dust Mite Elicits Allergic Airway Inflammation via a GM-CSF-Mediated Mechanism. Journal of Immunology. 173:6384-6392. 2004
- The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clinical and Experimental Immunology. 138:213-220. 2004
- Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation. International Journal of Biochemistry and Cell Biology International Journal of Biochemistry. 36:1573-1584. 2004
- Transient Corticosteroid Treatment Permanently Amplifies the Th2 Response in a Murine Model of Asthma. Journal of Immunology. 172:4995-5005. 2004
- Continuous Exposure to House Dust Mite Elicits Chronic Airway Inflammation and Structural Remodeling. American Journal of Respiratory and Critical Care Medicine. 169:378-385. 2004
- Interleukin-13–Dependent Expression of Matrix Metalloproteinase-12 Is Required for the Development of Airway Eosinophilia in Mice. American Journal of Respiratory Cell and Molecular Biology. 30:84-90. 2004
- GM-CSF and Dendritic Cells in Allergic Airway Inflammation: Basic Mechanisms and Prospects for Therapeutic Intervention. Current Drug Targets: Inflammation and Allergy Inflammation and Allergy - Drug Targets. 2:279-292. 2003
- The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses. Nature Immunology. 4:899-906. 2003
- Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses. Nature Immunology. 4:765-772. 2003
- Murine models of asthma. European Respiratory Journal European Respiratory Journal, Supplement. 22:374-382. 2003
- Impact of intranasal budesonide on immune inflammatory responses and epithelial remodeling in chronic upper airway inflammation. Journal of Allergy and Clinical Immunology. 112:37-44. 2003
- Evaluation of Inducible Costimulator/B7-Related Protein-1 as a Therapeutic Target in a Murine Model of Allergic Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. 28:722-730. 2003
- Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization. Journal of Allergy and Clinical Immunology. 111:1076-1086. 2003
- Chronic Exposure to Innocuous Antigen in Sensitized Mice Leads to Suppressed Airway Eosinophilia That Is Reversed by Granulocyte Macrophage Colony-Stimulating Factor. Journal of Immunology. 169:3499-3506. 2002
- Chronic exposure to innocuous leads to suppressed airway antigen in sensitized mice eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. Journal of Immunology. 169:3499-3506. 2002
- Granulocyte Macrophage Colony–Stimulating Factor–Driven Respiratory Mucosal Sensitization Induces Th2 Differentiation and Function Independently of Interleukin-4. American Journal of Respiratory Cell and Molecular Biology. 27:428-435. 2002
- On the generation of allergic airway diseases: from GM-CSF to Kyoto. Trends in Immunology Immunology Today. 23:396-402. 2002
- Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clinical and Experimental Allergy. 32:411-421. 2002
- Temporal–Spatial Analysis of the Immune Response in a Murine Model of Ovalbumin-Induced Airways Inflammation. American Journal of Respiratory Cell and Molecular Biology. 25:326-334. 2001
- Generation of experimental allergic airways inflammation in the absence of draining lymph nodes. Journal of Clinical Investigation. 108:577-583. 2001
- Cytokine Therapeutics for Asthma: An Appraisal of Current Evidence and Future Prospects. Current Pharmaceutical Design. 7:1059-1081. 2001
- Expression of the Th1 Chemokine IFN-γ-Inducible Protein 10 in the Airway Alters Mucosal Allergic Sensitization in Mice. Journal of Immunology. 166:2750-2759. 2001
- ICOS is essential for effective T-helper-cell responses. Nature Nature: New biology. 409:105-109. 2001
- Determinants of the immune-inflammatory response in allergic airway inflammation: Overview of antigen presentation and cellular activation. Journal of Allergy and Clinical Immunology. 106:S206-S212. 2000
- Eosinophilopoiesis in A Murine Model of Allergic Airway Eosinophilia: Involvement of Bone Marrow IL-5 and IL-5 Receptor α. Journal of Immunology. 165:4040-4050. 2000
- IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure. Allergy: European Journal of Allergy and Clinical Immunology. 55:749-756. 2000
- IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization. Proceedings of the National Academy of Sciences of the United States of America. 97:6007-6012. 2000
- Interleukin-10 Gene Transfer to the Airway Regulates Allergic Mucosal Sensitization in Mice. American Journal of Respiratory Cell and Molecular Biology. 21:586-596. 1999
- Regulation of Allergic Mucosal Sensitization by Interleukin-12 Gene Transfer to the Airway. American Journal of Respiratory Cell and Molecular Biology. 21:317-326. 1999
- Replication-Defective Adenovirus Infection ReducesHelicobacter felis Colonization in the Mouse in a Gamma Interferon- and Interleukin-12-Dependent Manner. Infection and Immunity. 67:4539-4544. 1999
- A Randomized Controlled Trial on the Effect of Inhaled Corticosteroids on Airways Inflammation in Adult Cigarette Smokers. Chest. 115:1271-1277. 1999
- Cytokines and pulmonary inflammatory and immune diseases.. Histology and Histopathology. 14:185-201. 1999
- Eosinophil activation in the tissue: synthetic steroid, budesonide, effectively inhibits the survival of eosinophils isolated from peripheral blood but not nasal polyp tissues.. Journal of Clinical and Laboratory Immunology. 51:39-53. 1999
- Adenoviral infection inhibits allergic airways inflammation in mice. Clinical and Experimental Allergy. 28:1581-1590. 1998
- GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.. Journal of Clinical Investigation. 102:1704-1714. 1998
- Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.. Journal of Clinical Investigation. 102:1132-1141. 1998
- Compartmentalized transgene expression of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) in mouse lung enhances allergic airways inflammation. Clinical and Experimental Immunology. 113:157-165. 1998
- Eosinophilia in antigen-induced airways inflammation.. Canadian Respiratory Journal. 5 Suppl A:31A-35A. 1998
- Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.. Journal of Clinical Investigation. 101:1342-1353. 1998
- Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans. Human Gene Therapy. 9:541-551. 1998
- IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.. Journal of Clinical Investigation. 101:311-320. 1998
- Bronchial myofibroblasts and tissue remodelling in asthma.. Canadian Respiratory Journal. 5:59-61. 1998
- Expression of Cytokine Receptors and HLA in Nasal Epithelial Cells.. Practica Otologica. 91:91-97. 1998
- Effect of Regular Inhaled Albuterol on Allergen-induced Late Responses and Sputum Eosinophils in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 156:1738-1745. 1997
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. Pneumologie. 51:396. 1997
- Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation.. American Journal of Respiratory Cell and Molecular Biology. 16:510-520. 1997
- Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia. Gene Therapy. 4:140-149. 1997
- Interleukin-4 synthesis by eosinophils in nasal polyps. Oto-Rhino-Laryngology Tokyo. 40:78-84. 1997
- Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation.. American Journal of Respiratory and Critical Care Medicine. 154:1267-1271. 1996
- Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation.. American Journal of Respiratory Cell and Molecular Biology. 15:404-409. 1996
- GM-CSF, IL-8, IL-1R, TNF-alpha R, and HLA-DR in nasal epithelial cells in allergic rhinitis.. American Journal of Respiratory and Critical Care Medicine. 153:1675-1681. 1996
- CD40 expression by human peripheral blood eosinophils.. Journal of Clinical Investigation. 97:1761-1766. 1996
- Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation. Journal of Leukocyte Biology. 59:481-488. 1996
- Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells.. Journal of Clinical Investigation. 97:1122-1128. 1996
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.. Journal of Clinical Investigation. 97:1102-1110. 1996
- Interleukin-3 in bronchial biopsies from nonasthmatics and patients with mild and allergen-induced asthma.. American Journal of Respiratory and Critical Care Medicine. 153:350-355. 1996
- Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma.. American Journal of Respiratory Cell and Molecular Biology. 13:639-647. 1995
- Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils.. Journal of Immunology. 155:3234-3244. 1995
- Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma.. American Journal of Respiratory and Critical Care Medicine. 151:1915-1924. 1995
- Increased survival of nasal polyp eosinophils. Immunology Letters. 45:219-221. 1995
- Survival of Eosinophils Isolated from Nasal Polyps. Oto-Rhino-Laryngology Tokyo. 38:574-581. 1995
- Immune-inflammatory functions of fibroblasts. European Respiratory Journal European Respiratory Journal, Supplement. 7:2212-2222. 1994
- Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.. American Journal of Respiratory Cell and Molecular Biology. 11:733-741. 1994
- Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.. Journal of Immunology. 153:4059-4069. 1994
- Nasal polyp inflammation. Effect of topical nasal steroid.. American Journal of Respiratory and Critical Care Medicine. 150:1094-1100. 1994
- Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. European Respiratory Journal European Respiratory Journal, Supplement. 7:1576-1584. 1994
- TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis).. Journal of Immunology. 153:2278-2289. 1994
- Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils.. Journal of Experimental Medicine. 180:711-715. 1994
- Growth and Colony-Stimulating Factors Mediate Eosinophil Fibroblast Interactions in Chronic Airway Inflammationa. Annals of the New York Academy of Sciences. 725:83-90. 1994
- Immunocytochemical detection of granulocyte-macrophage colony-stimulating factor and eosinophil cationic protein in sputum cells. Journal of Allergy and Clinical Immunology. 93:945-947. 1994
- Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation.. American Journal of Respiratory Cell and Molecular Biology. 10:148-153. 1994
- Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue. Clinical and Experimental Immunology. 95:343-350. 1994
- Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue.. American Journal of Pathology. 143:1009-1015. 1993
- CYTOKINES .4. CYTOKINES AND PULMONARY FIBROSIS. Thorax. 48:931-935. 1993
- Cytokines and pulmonary fibrosis.. Thorax. 48:931-935. 1993
- Lipopolysaccharide Induces Expression of Granulocyte/Macrophage Colony-stimulating Factor, Interleukin-8, and Interleukin-6 in Human Nasal, but Not Lung, Fibroblasts: Evidence for Heterogeneity within the Respiratory Tract. American Journal of Respiratory Cell and Molecular Biology. 9:255-263. 1993
- Cytokines in lung and airways fibrosis.. Regional immunology. 5:201-206. 1993
- Mast Cells and Fibrosis—Who's on First?. American Journal of Respiratory Cell and Molecular Biology. 8:7-8. 1993
- Bronchial Epithelial Cell-derived Cytokines (G-CSF and GM-CSF Promote the Survical of Peripheral Blood NeutrophilsIn Vitro. American Journal of Respiratory Cell and Molecular Biology. 7:507-514. 1992
- Effector Role of the Epithelial Compartment in Inflammational. Annals of the New York Academy of Sciences. 664:180-189. 1992
- Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes.. Journal of Rheumatology. 19:1065-1069. 1992
- Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1).. Journal of Clinical Investigation. 89:1662-1668. 1992
- IL-1 beta and IL-6 gene expression in alveolar macrophages: modulation by extracellular matrices. American Journal of Physiology - Lung Cellular and Molecular Physiology. 262:L600-L605. 1992
- IL-1-BETA AND IL-6 GENE-EXPRESSION IN ALVEOLAR MACROPHAGES - MODULATION BY EXTRACELLULAR MATRICES. American Journal of Physiology. 262:L600-L605. 1992
- FIBROBLASTS AND OTHER STRUCTURAL CELLS IN AIRWAY INFLAMMATION. American Review of Respiratory Disease. 145:S14-S17. 1992
- Fibroblasts and Other Structural Cells in Airway Inflammation. American Review of Respiratory Disease. 145:S14-S17. 1992
- Human Upper Airway Structural Cell-derived Cytokines Support Human Peripheral Blood Monocyte Survival: A Potential Mechanism for Monocyte/Macrophage Accumulation in the Tissue. American Journal of Respiratory Cell and Molecular Biology. 6:212-218. 1992
- Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF) Gene Expression by Eosinophils in Nasal Polyposis. American Journal of Respiratory Cell and Molecular Biology. 5:505-510. 1991
- Promotion of Eosinophil Survival by Human Bronchial Epithelial Cells and its Modulation by Steroids. American Journal of Respiratory Cell and Molecular Biology. 4:525-531. 1991
- Monocyte-Macrophage Differentiation Induced by Human Upper Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. 4:255-263. 1991
- Human Upper Airway Epithelial Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Induces Histamine-Containing Cell Differentiation of Human Progenitor Cells. International Archives of Allergy and Immunology. 95:376-384. 1991
- Neutrophilic Differentiation Induced by Human Upper Airway Fibroblast-derived Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF). American Journal of Respiratory Cell and Molecular Biology. 4:11-17. 1991
- Structural Cell-Derived Cytokines in Allergic Inflammation. International Archives of Allergy and Immunology. 94:127-132. 1991
- Fibrosis pulmonar: perspectivas actuales. Archivos de Bronconeumologia. 25:336-344. 1989
- Human Lung Fibroblast-derived Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mediates Eosinophil SurvivalIn Vitro. American Journal of Respiratory Cell and Molecular Biology. 1:289-295. 1989
- LATE-PHASE AIRWAY REACTION AND INFLAMMATION. Journal of Allergy and Clinical Immunology. 83:521-524. 1989
- Late-phase airway reaction and inflammation. Journal of Allergy and Clinical Immunology. 83:521-524. 1989
- Hemopoietic function of the microenvironment in chronic airway inflammation.. Agents and Actions Supplements. 28:85-95. 1989
- Effect of histamine on proliferation of normal human adult lung fibroblasts.. Thorax. 43:552-558. 1988
- Solute Movement across the Alveolar-Capillary Membrane after Intratracheally Administered Bleomycin in Rats. American Review of Respiratory Disease. 138:96-100. 1988
- SpontaneousIn VitroRelease of Alveolar-Macrophage Cytokines after the Intratracheal Instillation of Bleomycin in Rats: Characterization and Kinetic Studies. American Review of Respiratory Disease. 137:1135-1140. 1988
- Heterogeneous Proliferative Characteristics of Human Adult Lung Fibroblast Lines and Clonally Derived Fibroblasts from Control and Fibrotic Tissue. American Review of Respiratory Disease. 137:579-584. 1988
- Lung epithelial permeability in sarcoidosis.. Sarcoidosis. 4:116-121. 1987
- Alveolar Macrophage/Peripheral Blood Monocyte-Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts. Journal of Leukocyte Biology. 42:51-60. 1987
- Evaluation of lung epithelial permeability. European Journal of Nuclear Medicine and Molecular Imaging European Journal of Nuclear Medicine. 13:S58-S62. 1987
- MAST-CELL INVOLVEMENT IN VARIOUS INFLAMMATORY PROCESSES. American Review of Respiratory Disease. 135:S5-S8. 1987
- Mast cell involvement in various inflammatory processes.. American Review of Respiratory Disease. 135:S5-S8. 1987
- Methodologic considerations in mucociliary clearance and lung epithelial absorption measurements. European Journal of Nuclear Medicine and Molecular Imaging European Journal of Nuclear Medicine. 13:S45-S52. 1987
- ZIEHLS DIAGNOSTIC EVALUATION IN HEMOPTYSIS. Medicina Clinica. 70:239-240. 1978
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chapter
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conference paper
- Ara h 1 Peptide Immunotherapy Protects Against Peanut-Induced Anaphylaxis in a Dose-Dependent Manner. Journal of Allergy and Clinical Immunology. AB410-AB410. 2016
- Intestinal Microbiota Modulates Immune Responses to Dietary Gluten. Digestive Diseases and Sciences. 2550-2550. 2015
- Ara h 1 Peptide Immunotherapy Ameliorates Peanut-Induced Anaphylaxis. Journal of Allergy and Clinical Immunology. AB158-AB158. 2015
- Intracellular IL-1 alpha modulates peanut-induced anaphylaxis in a model of skin sensitisation. Allergy: European Journal of Allergy and Clinical Immunology. 18-18. 2014
- Mast cells infiltrate the alveolar parenchyma in young children with respiratory viral infections. European Respiratory Journal European Respiratory Journal, Supplement. 2014
- Comprehensive Metabolomic Analysis Identifies Uric Acid As a Critical Mediator Of Peanut Sensitization. Journal of Allergy and Clinical Immunology. AB28-AB28. 2014
- Microbiota Regulates Eosinophils In The Small Intestine. Journal of Allergy and Clinical Immunology. AB159-AB159. 2014
- Initiation of food allergy by a CD4(+) T cell-intrinsic IL-4 program, controlled by OX40L. Journal of Immunology. 2013
- Influence of Interleukin-13 in 5-HT Synthesis and Severity of Experimental Colitis. Gastroenterology. S26-S26. 2011
- The Epithelial-Derived Signals TSLP, IL-25 And IL-33 Converge On OX40L To Elicit House Dust Mite-Induced Allergic Airway Inflammation In Mice. American Journal of Respiratory and Critical Care Medicine. A2861-A2861. 2011
- The Epithelial-derived Cytokines TSLP, IL-33, and IL-25 Converge on OX40L to Elicit Peanut Allergy and Anaphylaxis in Mice. Journal of Allergy and Clinical Immunology. AB2-AB2. 2011
- Distinct Responsiveness To Allergen In Infant And Adult Mice Is Linked To Differential Myeloid Dendritic Cell And T Regulatory Cell Populations In The Lung. American Journal of Respiratory and Critical Care Medicine. 2011
- Evolution Of Immune-Suppressive And Immune-Responsive Capacities In The Lung During Development In Mice. American Journal of Respiratory and Critical Care Medicine. 2011
- Influenza-A Infection Alters the Immune Responsiveness to House Dust Mite in Neonatal Mice and Accelerates the Onset of Airway Remodeling. American Journal of Respiratory and Critical Care Medicine. 2010
- Modeling Of House Dust Mite-Induced Chronic Airway Eosinophilia. American Journal of Respiratory and Critical Care Medicine. 2010
- IL-13 Plays a Critical Role in Development of Enterochromaffin Cell Hyperplasia and Production of Serotonin. Gastroenterology. A235-A235. 2009
- Concurrent Blockade of Platelet Activating Factor and Histamine Prevents Life-threatening Peanut-induced Anaphylactic Reactions. Journal of Allergy and Clinical Immunology. S141-S141. 2009
- GM-CSF Overexpression in the Lung Changes Immune Susceptibility and Responsiveness to House Dust Mite Exposure.. American Journal of Respiratory and Critical Care Medicine. 2009
- House Dust Mite-Induced Allergic Airway Remodeling Develops Independently of Eosinophils. American Journal of Respiratory and Critical Care Medicine. 2009
- Modeling of HDM-Induced Chronic Airway Eosinophilia.. American Journal of Respiratory and Critical Care Medicine. 2009
- Ozone Exposure Can Facilitate Allergen Sensitization and Enhance the Allergic Response to House Dust Mite in a Mouse Model. American Journal of Respiratory and Critical Care Medicine. 2009
- Development of an Algorithm to Better Predict Clinical Responsiveness to Peanut. Journal of Allergy and Clinical Immunology. S97-S97. 2008
- Understanding Immunological Pathways of Peanut-induced Anaphylaxis. Journal of Allergy and Clinical Immunology. 524-524. 2007
- Experimental modeling and regulation of peanut-induced anaphylaxis. ACS National Meeting Book of Abstracts. 355-355. 2006
- Expression of GM-CSF in the airway drives Th2 differentiation and effector function in mice exposed to ragweed intranasally. Journal of Allergy and Clinical Immunology. S296-S297. 2002
- IL-10 inhibits allergen-specific TH2 cytokine production by human peripheral blood mononuclear cells from patients with ragweed allergies. Journal of Allergy and Clinical Immunology. S66-S66. 2002
- Molecular basis of allergic airways inflammation: Geographical considerations. FASEB Journal. A55-A55. 2001
- IL-10 gene transfer downregulates allograft tracheal transplant induced IL-2 gene expression. American Journal of Respiratory and Critical Care Medicine. A275-A275. 1999
- Increased IL-5-production by T-cells and non-T-cells in bone-marrow after airway allergen exposure. American Journal of Respiratory and Critical Care Medicine. A98-A98. 1999
- Immunomodulation of Helicobacter felis colonization of the mouse stomach. Gastroenterology. A935-A935. 1998
- Dose-dependent increase in bone-marrow eosinophil content after repeated airway allergen exposure in sensitised mice.. Journal of Allergy and Clinical Immunology. S34-S34. 1998
- ONCOSTATIN-M INHIBITS TYPE-1 PLASMINOGEN-ACTIVATOR INHIBITOR SYNTHESIS IN CULTURE HUMAN ENDOTHELIUM. Thrombosis and Haemostasis. 1128-1128. 1995
- ONCOSTATIN-M INHIBITS NEUTROPHIL INFLUX IN LPS-INDUCED ACUTE LUNG INFLAMMATION IN SPRAGUE-DAWLEY RATS. FASEB Journal. A492-A492. 1995
- LOCALIZATION OF INTERLEUKIN-4 IN EOSINOPHILS IN NASAL POLYPS AND ASTHMATIC BRONCHIAL-MUCOSA. Journal of Allergy and Clinical Immunology. 220-220. 1995
- SURFACTANT DOWN-REGULATES HUMAN MONOCYTE AND NEUTROPHIL RESPONSES TO HYPEROXIA. Pediatric Research. A20-A20. 1994
- SURFACTANT DOWN-REGULATES HUMAN MONOCYTE AND NEUTROPHIL RESPONSES TO HYPEROXIA. Pediatric Research. A394-A394. 1994
- IL-10 INHIBITS IL-6 PRODUCTION BY RAT PERITONEAL MAST-CELLS. FASEB Journal. A497-A497. 1994
- CYTOKINES AND HLA IMMUNOLOCALIZATION OF NASAL EPITHELIAL-CELLS. Journal of Allergy and Clinical Immunology. 270-270. 1994
- EFFECT OF BUDESONIDE (B) ON THE SURVIVAL OF EOSINOPHILS (EO) FROM BOTH PERIPHERAL-BLOOD AND NASAL POLYP (NP) TISSUES. Journal of Allergy and Clinical Immunology. 216-216. 1994
- CYTOKINE DETECTION IN THE SPUTUM OF SMOKERS WITH MINIMAL AIR-FLOW LIMITATION [CAL]. American Review of Respiratory Disease. A865-A865. 1993
- DETECTION OF TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA) AND MACROPHAGE INFLAMMATORY PEPTIDE-2 (MIP-2) IN THE LUNG OF RATS EXPOSED TO A SINGLE INTRATRACHEAL INSTILLATION OF LIPOPOLYSACCHARIDE (LPS). American Review of Respiratory Disease. A730-A730. 1993
- ENHANCED CONSTITUTIVE SURVIVAL OF NASAL POLYP-DERIVED EOSINOPHILS EXVIVO - ROLE OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF). American Review of Respiratory Disease. A821-A821. 1993
- GRANULOCYTE MACROPHAGE-COLONY-STIMULATING FACTOR AND EOSINOPHIL CATIONIC PROTEIN IN BRONCHIAL BIOPSIES - COMPARISONS BETWEEN MILD ASTHMATICS AND NON-ASTHMATICS. American Review of Respiratory Disease. A783-A783. 1993
- IMMUNOCYTOCHEMICAL DETECTION OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF), INTERLEUKIN-8 (IL-8) AND TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA) IN SPUTUM CELLS FROM PATIENTS WITH ASTHMA. American Review of Respiratory Disease. A786-A786. 1993
- INCREASED LOCALIZATION OF CD11B IN BRONCHIAL BIOPSIES FROM MILD ASTHMATICS COMPARED TO NON-ASTHMATICS. American Review of Respiratory Disease. A519-A519. 1993
- INTERLEUKIN-8 SECRETION BY GASTRIC EPITHELIUM FOLLOWING HELICOBACTER-PYLORI INFECTION INVITRO. Gastroenterology. A687-A687. 1993
- PLATELET-DERIVED GROWTH FACTOR-B (PDGF-B) GENE-EXPRESSION BY EOSINOPHILS IN CHRONICALLY INFLAMED UPPER AIRWAY TISSUES. American Review of Respiratory Disease. A822-A822. 1993
- SEQUENTIAL EXPRESSION OF CYTOKINES IN LUNG TISSUES FROM RATS EXPOSED TO CADMIUM CHLORIDE (CDCL2). American Review of Respiratory Disease. A734-A734. 1993
- THE PRECURSOR OF ELAFIN (PRE-ELAFIN) - GENE STRUCTURE AND REGULATION. American Review of Respiratory Disease. A678-A678. 1993
- EFFECTOR FUNCTION OF TISSUE STRUCTURAL CELLS IN INFLAMMATION. ASTHMA. 211-225. 1993
- GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF) IN NASAL POLYPS (NP) AND TURBINATE MUCOSA AND EFFECTS OF TOPICAL STEROID. Journal of Allergy and Clinical Immunology. 210-210. 1993
- ISOLATION OF AN ENRICHED ACTIVATED EOSINOPHIL (E-PHI) FRACTION FROM HUMAN NASAL POLYP (NP) TISSUES. Journal of Allergy and Clinical Immunology. 157-157. 1993
- Microenvironmental control of inflammatory cell differentiation. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 16. 1993
- EFFECT OF RHEUMATOID-ARTHRITIS SERUM (RA-SE) AND SYNOVIAL-FLUID (-SF) ON IL-8 AND GM-CSF PRODUCTION BY HUMAN SYNOVIOCYTES (SYN). FASEB Journal. A1898-A1898. 1992
- THE EFFECT OF NASAL POLYP STRUCTURAL CELL CONDITIONED MEDIA ON MAST-CELL MEDIATOR EXPRESSION. FASEB Journal. A1723-A1723. 1992
- DEPLETION OF LYMPHOCYTES-T AND EOSINOPHILS (EO) IN NASAL POLYPS (NP) TREATED BY TOPICAL STEROID. Journal of Allergy and Clinical Immunology. 221-221. 1992
- EOSINOPHILS, BASOPHILS AND MAST-CELLS IN THE AIRWAYS - INFLUENCE OF THE TISSUE MICROENVIRONMENT. HIGHLIGHTS IN ALLERGY AND CLINICAL IMMUNOLOGY. 95-100. 1992
- Microenvironmental Control of Inflammatory Cell Differentiation. International Archives of Allergy and Immunology. 330-332. 1992
- PROFILE OF EOSINOPHIL CYTOKINE RESPONSES IN HYPEREOSINOPHILIC SYNDROME (HES) - LACK OF EFFECT OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR. Journal of Allergy and Clinical Immunology. 160-160. 1992
- REGULATION OF PROTEASE AND CYTOKINE EXPRESSION IN A HUMAN MAST-CELL LINE (HMC-1) - EFFECT OF NASAL POLYP STRUCTURAL CELL-DERIVED CONDITIONED MEDIA. Journal of Allergy and Clinical Immunology. 246-246. 1992
- TISSUE PRODUCTION OF CYTOKINES IN ALLERGY. PROGRESS IN ALLERGY AND CLINICAL IMMUNOLOGY, VOL 2, KYOTO. 513-517. 1992
- THE LATE ASTHMATIC RESPONSE (LAR) AND THE TISSUE DRIVEN RESPONSE (TDR). ADVANCES IN ASTHMOLOGY 1990. 247-250. 1991
- MODULATION OF UPPER AIRWAY INFLAMMATION BY FIBROBLAST AND EPITHELIAL-CELL DERIVED CYTOKINES. Clinical Research. A239-A239. 1989
- PDGF EXPRESSION IN HUMAN NEONATAL PULMONARY FIBROBLASTS FOLLOWING HYPEROXIA. Pediatric Research. A317-A317. 1989
- EPITHELIAL-CELLS DERIVED FROM NASAL POLYPS AND INFERIOR TURBINATE TISSUES PRODUCE NEUTROPHILIC AND MONOCYTIC DIFFERENTIATING ACTIVITY. Journal of Allergy and Clinical Immunology. 299-299. 1989
- FIBROBLASTS DERIVED FROM HUMAN NASAL TISSUES PRODUCE NEUTROPHILIC AND BASOPHILIC DIFFERENTIATING FACTORS INCLUDING GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF). Journal of Allergy and Clinical Immunology. 300-300. 1989
- MODULATION OF PGE2 RELEASE AND PROCOLLAGEN MESSENGER-RNA EXPRESSION IN HUMAN-LUNG FIBROBLASTS BY PERIPHERAL-BLOOD MONOCYTE SUPERNATANTS. Australian and New Zealand Journal of Medicine. 527-527. 1988
- MACROPHAGE DERIVED IL-1 AND HEPATOCYTE STIMULATING FACTOR (HSF) ARE DISTINCT ENTITIES THAT INDUCE ACUTE PHASE PROTEIN-SYNTHESIS. Journal of Leukocyte Biology. 274-274. 1986
- ALVEOLAR MACROPHAGE ACTIVATION IN BRONCHOPULMONARY DYSPLASIA. American Review of Respiratory Disease. A207-A207. 1986
- CHARACTERISTICS OF HUMAN ADULT LUNG FIBROBLAST STRAINS AND CLONALLY-DERIVED LINES FROM NORMAL AND FIBROTIC TISSUE. American Review of Respiratory Disease. A36-A36. 1986
- HUMAN-LUNG FIBROBLASTS EXPRESS AN H2 HISTAMINE-RECEPTOR WHICH CAN MODULATE INVITRO PROLIFERATION. American Review of Respiratory Disease. A35-A35. 1986
- LUNG EPITHELIAL PERMEABILITY IN PATIENTS WITH INTERSTITIAL LUNG-DISEASE - INDICATOR OF PARENCYMAL LUNG INJURY. American Review of Respiratory Disease. A18-A18. 1986
- ALVEOLAR MACROPHAGE FACTORS MODULATE THE INVITRO RESPONSE OF LYMPHOCYTES, FIBROBLASTS AND HEPATOCYTES. Journal of Leukocyte Biology. 411-411. 1984
- BRONCHIAL HYPERREACTIVITY (BH) IN ASYMPTOMATIC NON-SMOKERS. European Journal of Respiratory Diseases. 103-103. 1982
- BRONCHIAL HYPERREACTIVITY AFTER ADULT RESPIRATORY DISTRESS SYNDROME. Critical Care Medicine. 149-149. 1981