Journal article
As bases neurobiológicas do transtorno bipolar
Abstract
In this article, the authors review relevant aspects related to the neurobiological basis of bipolar disorder. This illness has been associated with complex biochemical and molecular changes in brain circuits linked to neurotransmission and intracellular signal transduction pathways, and changes on neurons and glia have been proposed to be directly associated with clinical presentation of mania and depression. In the same context, dysfunctions …
Authors
Machado-Vieira R; Bressan RA; Frey B; Soares JC
Journal
Archives of Clinical Psychiatry, Vol. 32, No. suppl 1, pp. 28–33
Publisher
FapUNIFESP (SciELO)
DOI
10.1590/s0101-60832005000700005
ISSN
0101-6083