Journal article
Comparative effectiveness and safety of direct acting oral anticoagulants in nonvalvular atrial fibrillation for stroke prevention: a systematic review and meta-analysis
Abstract
Purpose:To systematically review available evidence of indirect comparisons from RCTs and direct comparisons from observational studies regarding the comparative effectiveness and safety of DOACs in patients with AF. Methods: Electronic databases including EMBASE, MEDLINE, and PUBMED were searched up to June 5th, 2020. Primary endpoints included effectiveness (stroke or systemic embolism [SE]) and safety (major bleeding) outcomes. Bucher …
Authors
Zhang J; Wang X; Liu X; Larsen TB; Witt DM; Ye Z; Thabane L; Li G; Lip GYH
Journal
European Journal of Epidemiology, Vol. 36, No. 8, pp. 793–812
Publisher
Springer Nature
Publication Date
August 2021
DOI
10.1007/s10654-021-00751-7
ISSN
0393-2990