Journal article
Mitochondria’s role in sleep: Novel insights from sleep deprivation and restriction studies
Abstract
OBJECTIVES/METHODS: The biology underlying sleep is not yet fully elucidated, but it is known to be complex and largely influenced by circadian rhythms. Compelling evidence supports of a link among circadian rhythms, sleep and metabolism, which suggests a role for mitochondria. These organelles play a significant role in energy metabolism via oxidative phosphorylation (OXPHOS) and several mitochondrial enzymes display circadian oscillations. …
Authors
Beaupre LMM; Brown GM; Braganza NA; Kennedy JL; Gonçalves VF
Journal
The World Journal of Biological Psychiatry, Vol. 23, No. 1, pp. 1–13
Publisher
Taylor & Francis
Publication Date
January 2, 2022
DOI
10.1080/15622975.2021.1907723
ISSN
1562-2975