Moving beyond threshold-based dichotomous classification to improve the accuracy in classifying non-responders Academic Article uri icon

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  • We examined maximal oxygen consumption responses following exercise training to demonstrate the limitations associated with threshold-based dichotomous classification of responders and non-responders and proposed alternative methods for classification. Specifically, we: 1) calculated individual probabilities of response, and 2) classified individuals using response confidence intervals (CI) and reference points of zero and a smallest worthwhile change of 0.5┬áMETs. Our findings support the use of individual probabilities and individual CIs to improve the accuracy in non-response classification.


  • Bonafiglia, Jacob T
  • Nelms, Matthew W
  • Preobrazenski, Nicholas
  • LeBlanc, Camille
  • Robins, Lauren
  • Lu, Simo
  • Lithopoulos, Alexander
  • Walsh, Jeremy
  • Gurd, Brendon J

publication date

  • November 2018