Peripheral Nervous System Manifestations Associated with COVID-19 Academic Article uri icon

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  • PURPOSE OF REVIEW: The present review discusses the peripheral nervous system (PNS) manifestations associated with coronavirus disease 2019 (COVID-19). RECENT FINDINGS: Nerve pain and skeletal muscle injury, Guillain-Barré syndrome, cranial polyneuritis, neuromuscular junction disorders, neuro-ophthalmological disorders, neurosensory hearing loss, and dysautonomia have been reported as PNS manifestations in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. COVID-19 has shown syndromic complexity. Not only does SARS-CoV-2 affect the central nervous system but also it involves the PNS. The PNS involvement may be due to dysregulation of the immune system attributable to COVID-19. Here we review the broad spectrum of PNS involvement of COVID-19.


  • Andalib, Sasan
  • Biller, José
  • Di Napoli, Mario
  • Moghimi, Narges
  • McCullough, Louise D
  • Rubinos, Clio A
  • O’Hana Nobleza, Christa
  • Azarpazhooh, M Reza
  • Catanese, Luciana
  • Elicer, Isabel
  • Jafari, Mostafa
  • Liberati, Fabrizio
  • Camejo, Claudia
  • Torbey, Michel
  • Divani, Afshin A

publication date

  • March 2021