Conference
Correlative Analyses of Patient and Clinical Characteristics Associated with Efficacy in Tisagenlecleucel-Treated Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients in the Juliet Trial
Abstract
Background: Tisagenlecleucel, an anti-CD19 chimeric antigen receptor (CAR)-T cell therapy, has demonstrated durable responses and a manageable safety profile in adult patients (pts) with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). We report the correlation of pre- and post-infusion factors and biomarkers with efficacy in tisagenlecleucel-treated pts with r/r DLBCL.
Methods: Results from JULIET, a global, …
Authors
Westin JR; Tam CS; Borchmann P; Jaeger U; McGuirk JP; Holte H; Waller EK; Jaglowski S; Bishop MR; Andreadis C
Volume
134
Publisher
American Society of Hematology
Publication Date
November 13, 2019
DOI
10.1182/blood-2019-129107
Conference proceedings
Blood
Issue
Supplement_1
ISSN
0006-4971