Anesthetics significantly increase the amount of intramembrane water in lipid membranes Journal Articles uri icon

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abstract

  • We studied the effect anesthetics on the water distribution in lipid bilayers by combining all-atom molecular dynamics simulations and neutron diffraction experiments. We found that anesthetics increase the intramembrane water content by up to 25%.

authors

  • Himbert, Sebastian
  • Zhang, Lili
  • Alsop, Richard J
  • Cristiglio, Viviana
  • Fragneto, Giovanna
  • Rheinstadter, Maikel

publication date

  • November 4, 2020