Anesthetics significantly increase the amount of intramembrane water in lipid membranes Academic Article uri icon

  •  
  • Overview
  •  
  • Identity
  •  
  • View All
  •  

abstract

  • We studied the effect anesthetics on the water distribution in lipid bilayers by combining all-atom molecular dynamics simulations and neutron diffraction experiments. We found that anesthetics increase the intramembrane water content by up to 25%.

authors

  • Himbert, Sebastian
  • Zhang, Lili
  • Alsop, Richard J
  • Cristiglio, Viviana
  • Fragneto, Giovanna
  • Rheinstadter, Maikel

publication date

  • September 1, 2020