Journal article
Age‐related changes to the satellite cell niche are associated with reduced activation following exercise
Abstract
Skeletal muscle satellite cell (SC) function and responsiveness is regulated, in part, through interactions within the niche, in which they reside. Evidence suggests that structural changes occur in the SC niche as a function of aging. In the present study, we investigated the impact of aging on SC niche properties. Muscle biopsies were obtained from the vastus lateralis of healthy young (YM; 21 ± 1 yr; n = 10) and older men (OM; 68 ± 1 yr; …
Authors
Nederveen JP; Joanisse S; Thomas ACQ; Snijders T; Manta K; Bell KE; Phillips SM; Kumbhare D; Parise G
Journal
The FASEB Journal, Vol. 34, No. 7, pp. 8975–8989
Publisher
Wiley
Publication Date
July 2020
DOI
10.1096/fj.201900787r
ISSN
0892-6638