Journal article
Actions of Hydrogen Sulfide and ATP-Sensitive Potassium Channels on Colonic Hypermotility in a Rat Model of Chronic Stress
Abstract
OBJECTIVE: To investigate the potential role of hydrogen sulphide (H(2)S) and ATP-sensitive potassium (K(ATP)) channels in chronic stress-induced colonic hypermotility.
METHODS: Male Wistar rats were submitted daily to 1 h of water avoidance stress (WAS) or sham WAS (SWAS) for 10 consecutive days. Organ bath recordings, H(2)S production, immunohistochemistry and western blotting were performed on rat colonic samples to investigate the role of …
Authors
Liu Y; Luo H; Liang C; Xia H; Xu W; Chen J; Chen M
Journal
PLOS ONE, Vol. 8, No. 2,
Publisher
Public Library of Science (PLoS)
Publication Date
2013
DOI
10.1371/journal.pone.0055853
ISSN
1932-6203