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Promotion of Eosinophil Survival by Human...
Journal article

Promotion of Eosinophil Survival by Human Bronchial Epithelial Cells and its Modulation by Steroids

Abstract

Accumulation of eosinophils in the bronchial tissue occurs in a variety of inflammatory disorders of the human airway. We asked whether airway epithelial cells released factors that could influence eosinophil survival and thus contribute to accumulation of these cells in the tissues. Using conditioned medium (CM) generated from cultured human bronchial epithelial cells (HBEC), we examined the in vitro survival of eosinophils isolated from human …

Authors

Cox G; Ohtoshi T; Vancheri C; Denburg JA; Dolovich J; Gauldie J; Jordana M

Journal

American Journal of Respiratory Cell and Molecular Biology, Vol. 4, No. 6, pp. 525–531

Publisher

American Thoracic Society

Publication Date

June 1991

DOI

10.1165/ajrcmb/4.6.525

ISSN

1044-1549