Journal article
Early cerebral small vessel disease and brain volume, cognition, and gait
Abstract
OBJECTIVE: Decline in cognitive function begins by the 40s, and may be related to future dementia risk. We used data from a community-representative study to determine whether there are age-related differences in simple cognitive and gait tests by the 40s, and whether these differences were associated with covert cerebrovascular disease on magnetic resonance imaging (MRI).
METHODS: Between 2010 and 2012, 803 participants aged 40 to 75 years in …
Authors
Smith EE; O'Donnell M; Dagenais G; Lear SA; Wielgosz A; Sharma M; Poirier P; Stotts G; Black SE; Strother S
Journal
Annals of Neurology, Vol. 77, No. 2, pp. 251–261
Publisher
Wiley
Publication Date
2 2015
DOI
10.1002/ana.24320
ISSN
0364-5134