Guidelines for the pharmacological treatment of anxiety disorders, obsessive–compulsive disorder and posttraumatic stress disorder in primary care Journal Articles uri icon

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  • OBJECTIVE: Anxiety disorders are frequently under-diagnosed conditions in primary care, although they can be managed effectively by general practitioners. METHODS: This paper is a short and practical summary of the World Federation of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) for the treatment in primary care. The recommendations were developed by a task force of 30 international experts in the field and are based on randomized controlled studies. RESULTS: First-line pharmacological treatments for these disorders are selective serotonin reuptake inhibitors (for all disorders), serotonin-norepinephrine reuptake inhibitors (for some) and pregabalin (for generalized anxiety disorder only). A combination of medication and cognitive behavior/exposure therapy was shown to be a clinically desired treatment strategy. CONCLUSIONS: This short version of an evidence-based guideline may improve treatment of anxiety disorders, OCD, and PTSD in primary care.


  • Van Ameringen, Michael
  • Bandelow, Borwin
  • Sher, Leo
  • Bunevicius, Robertas
  • Hollander, Eric
  • Kasper, Siegfried
  • Zohar, Joseph
  • Möller, Hans-Jürgen

publication date

  • June 2012