Journal article
THE ACTION OF HYDROXYUREA ON MOUSE L‐CELLS*
Abstract
ABSTRACT The toxic and inhibitory properties of hydroxyurea (HU) have been studied in asynchronous and synchronized populations of mouse L‐cells. Hydroxyurea is a potent growth inhibitor and appears to be specifically lethal for cells which are in the early part of S phase at the time the compound is introduced. Cells in late S phase, G 2 , mitosis and G 1 appear to progress normally around the cycle in the presence of the compound until they …
Authors
Bacchetti S; Whitmore GF
Journal
Cell Proliferation, Vol. 2, No. 3, pp. 193–211
Publisher
Wiley
Publication Date
July 1969
DOI
10.1111/j.1365-2184.1969.tb00230.x
ISSN
0960-7722