Journal article
A nontoxic system for 41.8 degrees C whole-body hyperthermia: results of a Phase I study using a radiant heat device.
Abstract
A Phase I study of whole-body hyperthermia (WBH) (52 treatments/12 patients) was completed with no significant clinical toxicity. The study incorporated a thermal dose escalation scheme from 39.5 degrees-41.8 degrees C for up to 151 min. A radiant-heat device was utilized for producing WBH. During WBH, patients were sedated; endotracheal intubation was not required. No changes in cardiovascular, respiratory, hematological, or biochemical …
Authors
Robins HI; Dennis WH; Neville AJ; Shecterle LM; Martin PA; Grossman J; Davis TE; Neville SR; Gillis WK; Rusy BF
Journal
Cancer Research, Vol. 45, No. 8, pp. 3937–3944
Publication Date
August 1985
ISSN
0008-5472