Three methods for minimally important difference: no relationship was found with the net proportion of patients improving

OBJECTIVE: To determine the impact on a responder type analysis of using three published methods to obtain the minimally important difference (MID) on the conclusion of a randomized controlled trial (RCT). STUDY DESIGN AND SETTING: Using data from an RCT of supportive-expressive group therapy (SEGT-intervention) vs. standard care (control) in women with metastatic breast cancer, we measured individual responsiveness to change according to three …