Coronary artery disease is a chronic medical condition associated with high mortality and morbidity. Among individuals with coronary artery disease, more than 50% have chronic stable angina. Recent evidence supports initial treatment with medical therapy, followed by revascularization, if indicated, in patients with chronic stable angina. The successful management of patients with chronic stable angina involves a combination of proven secondary preventative strategies, conventional medications for symptom relief, and, in some selected suitable patients, revascularization therapy.