Use of topotecan in pre-treated recurrent or relapsed ovarian cancer patients

Question: What is the role of topotecan in the treatment of patients with progressive or relapsed ovarian cancer who have previously been treated with platinum-containing first-line chemotherapy? Perspective: Evidence was collected and reviewed by two members of the Gynecology Disease Site Group (DSG) of the Cancer Care Ontario Practice Guidelines Initiative. This practice guideline report has been reviewed, discussed, and approved by the …