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Regional differences in the pattern of airway...
Journal article

Regional differences in the pattern of airway remodeling following chronic allergen exposure in mice

Abstract

BackgroundAirway remodeling present in the large airways in asthma or asthma models has been associated with airway dysfunction in humans and mice. It is not clear if airways distal to the large conducting airways have similar degrees of airway remodeling following chronic allergen exposure in mice. Our objective was to test the hypothesis that airway remodeling is heterogeneous by optimizing a morphometric technique for distal airways and …

Authors

Hirota JA; Ellis R; Inman MD

Journal

Respiratory Research, Vol. 7, No. 1,

Publisher

Springer Nature

Publication Date

December 2006

DOI

10.1186/1465-9921-7-120

ISSN

1465-9921