Canadian association of gastroenterology position statement: Hip fracture and proton pump inhibitor therapy -a 2013 update

There have been numerous studies investigating the risk of fracture with PPI therapy since the CAG position statement in 2008. These data, however, do not change the conclusions of the original position statement. Current data would not support particular care in prescribing PPI therapy due to concerns about risk of fracture. The risk is extremely modest and there is no persuasive evidence that even this risk is causal and the association could be spurious. As with all medications, PPIs should only be given when there are clear indications that the benefit of therapy outweighs the risk. © 2013 Pulsus Group Inc.