SU‐C‐211‐05: Improved Target Localization with Integrated X‐Ray/bioluminescent Tomography

Abstract

Purpose: Bioluminescence tomography (BLT) is a promising approach to guide focal irradiation of pre‐palpable tumors in small animals, but is limited in resolution. In this study, we investigate the use of x‐ray and diffuse optical tomography tomography to provide spatial and optical information about the object to improve BLT reconstruction. Methods: In a 3‐step approach, x‐ray CBCT is used first to provide the anatomic spatial information …