An Automatic MRI Brain Volume Alignment Tool

The location, size and shape of Multiple Sclerosis (MS) lesions are often used to diagnose and track disease progression. In order to effectively compare lesions in MRI stacks for the same patient imaged at intervals, these stacks must be aligned. This automatic alignment method was designed to minimize modification of segmented pixel values. The aligned lesion stacks can be browsed independently or in tandem. This should provide a valuable tool for computer-aided diagnosis and disease tracking.