Aspects of screw design for wet granulation extrusion
Abstract
This paper discusses our preliminary trials examining the particle size and particle shape of granules produced by different screw elements in a co-rotating twin-screw extruder. In general, conveying elements did not provide the necessary consolidation to allow large particles to grow in significant quantity, whereas the different mixing elements led to the large particles desired for tabletting. Granules from mixing elements varied from near-spherical to chains to grains to plate-like (disk) shapes depending on the type selected.