Quality by design in the pharmaceutical industry: Process modelling, monitoring and control using latent variable methods

The pharmaceutical industry has entered a new era. Attention is now being paid to real time process monitoring, real time process control, continuous improvement of processes, and quick product technology transfer. Terms like Quality by Design, Design Space, Control Strategy, Process Analytical technology, Process Signature reflect the current state. Multivariate Statistical Analysis has played an integral part in several industries, enabling …