Prediction of the migration behavior of analytes in capillary electrophoresis based on three fundamental parameters

The prediction of analyte migration behavior in capillary electrophoresis (CE) is essential for rapid method development. The dynamic complexation model, based on 1:1 interactions, was used to accurately predict the apparent electrophoretic mobilities and the migration times of a group of deoxyribonucleotides (dNPs) at various concentrations of β-cyclodextrin (β-CD). The electrophoretic mobility of the analyte, the electrophoretic mobility of …