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Nonspecific binding removal with ultrasonic...
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Nonspecific binding removal with ultrasonic microdevices

Abstract

Protein microarrays are high information density bioassays that, if accurate, provide information valuable in early disease diagnosis and biodefense applications. While elegant patterning methods exist, diagnostic validity is crippled by nonspecific binding and device fouling. Nonspecifically bound biomolecules create false signal, block sensor receptors, and foul detectors. As biomarker detection (electrochemical, gravimetric or optical) is …

Authors

Meyer GD; Moran-Mirabal J; Branch DW; Craighead HG

Volume

1

Pagination

pp. 19-21

Publication Date

January 1, 2005

Conference proceedings

Micro Total Analysis Systems Proceedings of Microtas 2005 Conference 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences