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Detection of Antimicrobial Resistance Using...
Journal article

Detection of Antimicrobial Resistance Using Proteomics and the Comprehensive Antibiotic Resistance Database: A Case Study

Abstract

PURPOSE: Antimicrobial resistance (AMR), especially multidrug resistance, is one of the most serious global threats facing public health. The authors proof-of-concept study assessing the suitability of shotgun proteomics as an additional approach to whole-genome sequencing (WGS) for detecting AMR determinants. EXPERIMENTAL DESIGN: Previously published shotgun proteomics and WGS data on four isolates of Campylobacter jejuni are used to perform …

Authors

Chen C; Clark CG; Langner S; Boyd DA; Bharat A; McCorrister SJ; McArthur AG; Graham MR; Westmacott GR; Van Domselaar G

Journal

Proteomics Clinical Applications, Vol. 14, No. 4,

Publisher

Wiley

Publication Date

July 2020

DOI

10.1002/prca.201800182

ISSN

1862-8346