Journal article
Optimizing Whole Brain Radiation Therapy Dose and Fractionation: Results From a Prospective Phase 3 Trial (NCCTG N107C [Alliance]/CEC.3)
Abstract
PURPOSE: Whole brain radiation therapy (WBRT) remains a commonly used cancer treatment, although controversy exists regarding the optimal dose/fractionation to optimize intracranial tumor control and minimize resultant cognitive deficits.
METHODS AND MATERIALS: NCCTG N107C [Alliance]/CEC.3 randomized 194 patients with brain metastases to either stereotactic radiosurgery alone or WBRT after surgical resection. Among the 92 patients receiving …
Authors
Trifiletti DM; Ballman KV; Brown PD; Anderson SK; Carrero XW; Cerhan JH; Whitton AC; Greenspoon J; Parney IF; Laack NN
Journal
International Journal of Radiation Oncology • Biology • Physics, Vol. 106, No. 2, pp. 255–260
Publisher
Elsevier
Publication Date
February 2020
DOI
10.1016/j.ijrobp.2019.10.024
ISSN
0360-3016