Journal article
Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals
Abstract
BACKGROUND: The precise age distribution and calculated stroke risk of screen-detected atrial fibrillation (AF) is not known. Therefore, it is not possible to determine the number needed to screen (NNS) to identify one treatable new AF case (NNS-Rx) (i.e., Class-1 oral anticoagulation [OAC] treatment recommendation) in each age stratum. If the NNS-Rx is known for each age stratum, precise cost-effectiveness and sensitivity simulations can be …
Authors
Lowres N; Olivier J; Chao T-F; Chen S-A; Chen Y; Diederichsen A; Fitzmaurice DA; Gomez-Doblas JJ; Harbison J; Healey JS
Journal
PLOS Medicine, Vol. 16, No. 9,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pmed.1002903
ISSN
1549-1277