Journal article
Circulating Tumor DNA Alterations in Advanced Urothelial Carcinoma and Association with Clinical Outcomes: A Pilot Study
Abstract
Cell-free circulating DNA (cfDNA) can be used for noninvasive profiling of tumor genomic aberrations. We hypothesized that molecular alterations may inform prognostication in advanced urothelial carcinoma (aUC). We evaluated 124 aUC patients who underwent cfDNA analysis using a 73-gene sequencing panel (Guardant360). The association of molecular alterations and clinical factors with overall survival (OS) and failure-free-survival (FFS) was …
Authors
Grivas P; Lalani A-KA; Pond GR; Nagy RJ; Faltas B; Agarwal N; Gupta SV; Drakaki A; Vaishampayan UN; Wang J
Journal
European Urology Oncology, Vol. 3, No. 5, pp. 695–699
Publisher
Elsevier
Publication Date
10 2020
DOI
10.1016/j.euo.2019.02.004
ISSN
2588-9311