Journal article
Quantifying Antibody Responses Induced by Antigen-Agnostic Immunotherapies
Abstract
As the development and clinical application of cancer immunotherapies continue to expand, so does the need for novel methods to dissect their mechanisms of action. Antibodies are important effector molecules in cancer therapies due to their potential to bind directly to surface-expressed antigens and facilitate Fc receptor-mediated uptake of antigens by antigen-presenting cells. Quantifying antibodies that are specific for defined antigens is …
Authors
van Vloten JP; Klafuric EM; Karimi K; McFadden G; Petrik JJ; Wootton SK; Bridle BW
Journal
Molecular Therapy — Methods & Clinical Development, Vol. 14, , pp. 189–196
Publisher
Elsevier
Publication Date
September 2019
DOI
10.1016/j.omtm.2019.06.010
ISSN
2399-6951