selected scholarly activity
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academic article
- AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma. Cancer Gene Therapy. 2019
- Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer. Clinical Cancer Research. 25:1624-1638. 2019
- Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine. BMC Research Notes. 11:428. 2018
- A Comparison of Toll-Like Receptor 5 and 21 Ligands as Adjuvants for a Formaldehyde Inactivated H9N2 Avian Influenza Virus Vaccine in Chickens. Viral Immunology. 31:605-612. 2018
- Examination of the effects of virus inactivation methods on the induction of antibody- and cell-mediated immune responses against whole inactivated H9N2 avian influenza virus vaccines in chickens. Vaccine. 36:3908-3916. 2018
- Production and Purification of High-Titer Newcastle Disease Virus for Use in Preclinical Mouse Models of Cancer. Molecular Therapy - Methods and Clinical Development. 9:181-191. 2018
- Hyperglycemia promotes insulin-independent ovarian tumor growth. Gynecologic Oncology. 149:361-370. 2018
- Maternal nutrient restriction impairs young adult offspring ovarian signaling resulting in reproductive dysfunction and follicle loss†. Biology of Reproduction. 98:664-682. 2018
- VEGF, FGF-2 and TGFβ expression in the normal and regenerating epidermis of geckos: implications for epidermal homeostasis and wound healing in reptiles. Journal of Anatomy. 232:768-782. 2018
- Enhancing Immune Responses to Cancer Vaccines Using Multi-Site Injections. Scientific Reports. 7:8322. 2017
- Low-dose metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than maximum tolerated dose delivery in the mouse†. Biology of Reproduction. 97:449-465. 2017
- Akt isoform specific effects in ovarian cancer progression. Oncotarget. 7:74820-74833. 2016
- Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer. Oncotarget. 7:47343-47365. 2016
- Maternal High-Fat Diet-Induced Loss of Fetal Oocytes Is Associated with Compromised Follicle Growth in Adult Rat Offspring1. Biology of Reproduction. 94:94. 2016
- Perinatal Administration of a Selective Serotonin Reuptake Inhibitor Induces Impairments in Reproductive Function and Follicular Dynamics in Female Rat Offspring. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 22:1297-1311. 2015
- Anti-angiogenic Therapy and Induction of Blood Vessel Normalization in the Treatment of Ovarian Cancer. Current Angiogenesis. 3:203-214. 2015
- Fetal Exposure to Sertraline Hydrochloride Impairs Pancreatic β-Cell Development. Endocrinology. 156:1952-1957. 2015
- Early Life Exposure to Undernutrition Induces ER Stress, Apoptosis, and Reduced Vascularization in Ovaries of Adult Rat Offspring1. Biology of Reproduction. 92:110. 2015
- Combined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy induces regression and significantly improves survival in a preclinical model of advanced stage epithelial ovarian cancer. FASEB Journal. 29:576-588. 2015
- The internet, identity and intellectual capital: a response to Dreyfus’s critique of e-learning. Ethics and Information Technology. 16:275-284. 2014
- Trophoblast Invasion and Blood Vessel Remodeling Are Altered in a Rat Model of Lifelong Maternal Obesity. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 21:648-657. 2014
- Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression. PLoS ONE. 9:e94595-e94595. 2014
- The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis. Reproductive Biology and Endocrinology. 12:21-21. 2014
- Challenges in Experimental Modeling of Ovarian Cancerogenesis. Methods in Molecular Biology. 1049:371-376. 2013
- Orthotopic, syngeneic mouse model to study the effects of epithelial-stromal interaction. Methods in Molecular Biology. 1049:409-423. 2013
- The impact of the ovarian microenvironment on the anti-tumor effect of SPARC on ovarian cancer1This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.. Biochemistry and Cell Biology. 90:96-107. 2012
- Adverse Fetal and Neonatal Outcomes Associated with a Life-Long High Fat Diet: Role of Altered Development of the Placental Vasculature. PLoS ONE. 7:e33370-e33370. 2012
- Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology. 39:37-42. 2012
- Low Levels of X-Inactive Specific Transcript in Somatic Cell Nuclear Transfer Embryos Derived from Female Bovine Freemartin Donor Cells. Sexual Development. 6:151-159. 2012
- ABT-898 Induces Tumor Regression and Prolongs Survival in a Mouse Model of Epithelial Ovarian Cancer. Molecular Cancer Therapeutics. 10:1876-1885. 2011
- Fetal and Neonatal Exposure to Nicotine Disrupts Postnatal Lung Development in Rats: Role of VEGF and Its Receptors. International Journal of Toxicology. 30:244-252. 2011
- Rapid Insulin-like Growth Factor-1-induced Changes in Granulosa Cell Thrombospondin-1 Expression In Vitro. Journal of Reproduction and Development. 57:76-83. 2011
- Regulation of thrombospondin-1 expression through AU-rich elements in the 3′UTR of the mRNA. Cellular and Molecular Biology Letters. 16:55-68. 2011
- The function of IGF-IR in NNK-mediated lung tumorigenesis. Lung Cancer. 71:11-18. 2011
- Preneoplastic changes persist after IGF-IR downregulation and tumor regression. Oncogene. 29:4779-4786. 2010
- Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis. Endocrine. 37:303-311. 2010
- The Thrombospondin-1 Mimetic ABT-510 Increases the Uptake and Effectiveness of Cisplatin and Paclitaxel in a Mouse Model of Epithelial Ovarian Cancer. Neoplasia. 12:275-283. 2010
- ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis. Molecular Cancer. 9:235-235. 2010
- Extracellular Matrix Proteins and Tumor Angiogenesis. Journal of Oncology. 2010:1-13. 2010
- The Role of Dysregulated Glucose Metabolism in Epithelial Ovarian Cancer. Journal of Oncology. 2010:1-13. 2010
- Effects of rosiglitazone on ovarian function and fertility in animals with reduced fertility following fetal and neonatal exposure to nicotine. Endocrine. 36:281-290. 2009
- Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis. Neoplasia. 11:672-682. 2009
- Reversibility and recurrence of IGF-IR-induced mammary tumors. Oncogene. 28:2152-2162. 2009
- Autocrine VEGF-A/KDR loop protects epithelial ovarian carcinoma cells from anoikis. International Journal of Cancer. 124:553-561. 2009
- ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Molecular Cancer Therapeutics. 8:64-74. 2009
- Rosiglitazone prevents diabetes by increasing beta-cell mass in an animal model of type 2 diabetes characterized by reduced beta-cell mass at birth. Diabetes, Obesity and Metabolism. 10:763-771. 2008
- Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor. Molecular Cancer Research Cell Growth and Differentiation. 6:819-828. 2008
- Epithelial–stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer. Gynecologic Oncology. 108:385-394. 2008
- Relationships Between Ultrasonographic Image Attributes, Histomorphology and Proliferating Cell Nuclear Antigen Expression of Bovine Antral Follicles and Corpora Lutea ex situ. Reproduction in Domestic Animals. 0:070824033729005-???. 2008
- cAMP response element–binding protein is expressed at high levels in human ovarian adenocarcinoma and regulates ovarian tumor cell proliferation. International Journal of Gynecological Cancer. 18:1248-1257. 2008
- Influence of dichlorodiphenylchloroethylene on vascular endothelial growth factor and insulin-like growth factor in human and rat ovarian cells. Reproductigve Toxicoloy. 24:359-364. 2007
- Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). Journal of Cellular Physiology. 210:807-818. 2007
- Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). Journal of Cellular Physiology. 210:807-818. 2007
- Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene. 26:1636-1644. 2007
- Fetal and Neonatal Exposure to Nicotine Disrupts Ovarian Function and Fertility in Adult Female Rats. Endocrine. 30:213-216. 2006
- Growth hormone and insulin-like growth factor gene expression prior to the development of the pituitary gland in rainbow trout (Oncorhynchus mykiss) embryos reared at two temperatures. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 143:514-522. 2006
- Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes. Diabetologia. 48:2661-2666. 2005
- Telomere length analysis in goat clones and their offspring. Molecular Reproduction and Development. 72:461-470. 2005
- Impact of Polychlorinated Biphenyls Contamination on Estrogenic Activity in Human Male Serum. Environmental Health Perspectives EHP Toxicogenomics. 113:1277-1284. 2005
- Thrombospondin and Vascular Endothelial Growth Factor Are Cyclically Expressed in an Inverse Pattern During Bovine Ovarian Follicle Development1. Biology of Reproduction. 72:1071-1078. 2005
- Prenatal Exposure to Nicotine Causes Postnatal Obesity and Altered Perivascular Adipose Tissue Function. Obesity Research Obesity. 13:687-692. 2005
- The Effects of In Utero and Lactational Exposure to Chloroform on Postnatal Growth and Glucose Tolerance in Male Wistar Rats. Endocrine. 25:223-228. 2004
- Leptin Enhances Oocyte Nuclear and Cytoplasmic Maturation via the Mitogen-Activated Protein Kinase Pathway. Endocrinology. 145:5355-5363. 2004
- Vascular Endothelial Growth Factor and Its Receptor, Flk-1/KDR, Are Cytoprotective in the Extravascular Compartment of the Ovarian Follicle. Endocrinology. 145:2896-2905. 2004
- Possible Effects of Polychlorinated Biphenyls and Organochlorinated Pesticides on the Thyroid after Long-term Exposure to Heavy Environmental Pollution. Journal of Occupational and Environmental Medicine. 45:526-532. 2003
- Expression of growth hormone and its transcription factor, Pit-1, in early bovine development. Molecular Reproduction and Development. 64:275-283. 2003
- Expression and Localization of Thrombospondin-1 and -2 and Their Cell-Surface Receptor, CD36, During Rat Follicular Development and Formation of the Corpus Luteum1. Biology of Reproduction. 67:1522-1531. 2002
- High Prevalence of Anti-Glutamic Acid Decarboxylase (Anti-GAD) Antibodies in Employees at a Polychlorinated Biphenyl Production Factory. Archives of Environmental Health Archives of Environmental and Occupational Health. 57:412-415. 2002
- Thrombin Generation and Presence of Thrombin Receptor in Ovarian Follicles1. Biology of Reproduction. 66:1350-1358. 2002
- Atmospheric mercury levels in the Slovak Republic. Chemosphere Chemosphere - Global Change Science. 45:801-806. 2001
- A Long-Term High-Carbohydrate Diet Causes an Altered Ontogeny of Pancreatic Islets of Langerhans in the Neonatal Rat. Pediatric Research. 49:84-92. 2001
- The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in rats.. Endocrinology. 141:1196-1208. 2000
- A Low Protein Diet Alters the Balance of Islet Cell Replication and Apoptosis in the Fetal and Neonatal Rat and Is Associated with a Reduced Pancreatic Expression of Insulin-Like Growth Factor-II. Endocrinology. 140:4861-4873. 1999
- A Low Protein Diet Alters the Balance of Islet Cell Replication and Apoptosis in the Fetal and Neonatal Rat and Is Associated with a Reduced Pancreatic Expression of Insulin-Like Growth Factor-II1. Endocrinology. 140:4861-4873. 1999
- Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.. Endocrinology. 140:2353-2363. 1999
- Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice. Journal of Endocrinology. 161:153-165. 1999
- Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas. Journal of Endocrinology. 160:305-317. 1999
- Growth factors and the regulation of fetal growth.. Diabetes Care. 21 Suppl 2:B60-B69. 1998
- Apoptosis in the Pancreatic Islet Cells of the Neonatal Rat Is Associated with a Reduced Expression of Insulin-Like Growth Factor II that May Act as a Survival Factor. Endocrinology. 139:2994-3004. 1998
- Apoptosis in the Pancreatic Islet Cells of the Neonatal Rat Is Associated with a Reduced Expression of Insulin-Like Growth Factor II that May Act as a Survival Factor*. Endocrinology. 139:2994-3004. 1998
- In defense of C.S. Lewis's analysis of God's goodness. International Journal for Philosophy of Religion. 36:45-56. 1994
- EVERY DOGMA MUST HAVE ITS DAY. Communication and Cognition. 24:137-148. 1991
- FREEDOM AS SELF-DETERMINATION IN THESUMMA THEOLOGIAE. Southern Journal of Philosophy. 27:87-100. 1989
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article
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conference paper
- Widespread Growth Factor Expression in the Reptilian Epidermis Indicates Roles During Homeostasis and Wound Healing. FASEB Journal. 2017
- Widespread Growth Factor Expression in the Reptilian Epidermis Indicates Roles During Homeostasis and Wound Healing. FASEB Journal. 2017
- 66. Recombinant Newcastle Disease Virus as an Oncolytic Therapy for Ovarian and Prostate Cancers. Molecular Therapy. S29-S29. 2016
- SUBCUTANEOUS ADMINISTRATION OF A THROMBOSPONDIN-1 MIMETIC PEPTIDE NORMALIZES TUMOR VASCULATURE, INCREASES DRUG UPTAKE AND INDUCES REGRESSION OF ADVANCED OVARIAN CANCER. Annals of Oncology. 29-30. 2012
- Abstract 409: The influence of chronic low grade systemic inflammation on the progression of epithelial ovarian cancer. Cancer Research. 2011
- Angiogenesis in the regenerating tail of the leopard gecko, Eublepharis macularius. FASEB Journal. 2011
- Maternal Obesity Results in Placental Hypoxia and Altered Mitochondral Function. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 123A-123A. 2011
- Maternal Obesity Results in Altered Placental Vascularization: The Role of Oxidative Stress. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 164A-164A. 2010
- The Role of Thrombospondin-1 (TSP-1) in Epithelial Ovarian Cancer.. Biology of Reproduction. 110-111. 2008
- In utero and lactational exposure to nicotine: Alterations to the intra-ovarian IGF system. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 74A-74A. 2008
- Concentration of insulin-like growth factor-I (IGF-1), leptin, growth hormone (GH), estradiol and progesterone (P-4) in follicular cysts of lactating dairy cattle. Theriogenology. 683-683. 2006
- In Utero and Lactational Exposure to Nicotine: Ovarian Effects. FERTILITY AND STERILITY. S384-S384. 2005
- Fetal exposure to water disinfection by-products alters postnatal growth and glucose homeostasis.. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 364A-364A. 2004
- Potential role of thrombospondin as an inhibitor of vascular endothelial growth factor expression in the ovary. Biology of Reproduction. 149-149. 2003
- Proliferative and cytoprotective roles for vascular endothelial growth factor in ovarian granulosa cells.. Biology of Reproduction. 233-233. 2003
- Expression and localization of vascular endothelial growth factor and angiopoietin-1 and their receptors FLT-1, FLK-1, and TIE-2 in bovine ovaries during follicular and luteal development.. Biology of Reproduction. 182-182. 2002
- Descartes on Divine Indifference and the Transworld Validity of the Eternal Truths. Southern Journal of Philosophy. 417-432. 1998
- Balance of islet cell birth and death of fetal and neonatal rats is altered by a low protein diet through mechanisms which include cell cycle kinetics. Diabetologia. A67-A67. 1998
- Insulin-like growth factors in the development of the pancreas. International Congress Series. 145-153. 1998