Estimating blood flow in skeletal muscle arteriolar trees reconstructed from in vivo data using the Fry approach

OBJECTIVE: To develop a computational method to accurately predict blood flow in skeletal muscle arteriolar trees in the absence of complete boundary data. METHODS: We used arteriolar trees in the rat GM muscle that were reconstructed from montages obtained via IVVM, and incorporated a recently published method for approximating unknown b.c.'s into our existing two-phase, steady-state blood flow model. For varying numbers of unknown b.c.'s, we …