Journal article
Acute and Chronic Effects of Airway Obstruction on Canine Left Ventricular Performance
Abstract
We used a canine model of chronic obstructive sleep apnea (OSA) to examine the effects of intermittent airway occlusion during sleep on left ventricular (LV) performance. Studies were performed in four dogs. The effects of acute airway occlusion on LV pressure and volume (on a background of chronic OSA) were determined with an impedance catheter and a high fidelity manometer. In conscious animals (n = 3), experiencing spontaneous episodes of …
Authors
PARKER JD; BROOKS D; KOZAR LF; RENDER-TEIXEIRA CL; HORNER RL; DOUGLAS BRADLEY T; PHILLIPSON EA
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 160, No. 6, pp. 1888–1896
Publisher
American Thoracic Society
Publication Date
December 1, 1999
DOI
10.1164/ajrccm.160.6.9807074
ISSN
1073-449X