Conference
Abstract 3694: The mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase as an inhibitory target for cancer therapeutics
Abstract
Abstract
The hypoxic and glycolytic environment of malignant cells facilitates high levels of reactive oxygen species (ROS) production. Breast, ovarian and prostate cancer etiology is associated with the ROS production, which are thought to play an important role in regulating the cancers cell growth, survival and metastasis. A potent and major cellular, however functional limited characterized source of ROS, is the …
Authors
Paschos A; Laflamme P; Singh G
Volume
70
Pagination
pp. 3694-3694
Publisher
American Association for Cancer Research (AACR)
Publication Date
April 15, 2010
DOI
10.1158/1538-7445.am10-3694
Conference proceedings
Cancer Research
Issue
8_Supplement
ISSN
0008-5472