Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study Academic Article uri icon

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abstract

  • BACKGROUND: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. OBJECTIVES: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. METHODS: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. RESULTS: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. CONCLUSION AND CLINICAL RELEVANCE: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.

authors

  • Keith, Paul
  • Menditto, Enrica
  • Costa, Elisio
  • Midão, Luis
  • Bosnic‐Anticevich, Sinthia
  • Novellino, Ettore
  • Bialek, Slawomir
  • Briedis, Vitalis
  • Mair, Alpana
  • Rajabian‐Soderlund, Rojin
  • Arnavielhe, Sylvie
  • Bedbrook, Anna
  • Czarlewski, Wienczyslawa
  • Annesi‐Maesano, Isabella
  • Anto, Josep M
  • Devillier, Philippe
  • De Vries, Govert
  • Keil, Thomas
  • Sheikh, Aziz
  • Orlando, Valentina
  • Larenas‐Linnemann, Désirée
  • Cecchi, Lorenzo
  • De Feo, Giulia
  • Illario, M
  • Stellato, Cristiana
  • Fonseca, Joao
  • Malva, Joao
  • Morais‐Almeida, Mario
  • Pereira, Ana Maria
  • Todo‐Bom, Ana Maria
  • Kvedariene, Violeta
  • Valiulis, Arunas
  • Bergmann, Karl Christian
  • Klimek, Ludger
  • Mösges, Ralph
  • Pfaar, Oliver
  • Zuberbier, Torsten
  • Cardona, Vicky
  • Mullol, Joaquim
  • Papadopoulos, Nikos G
  • Prokopakis, Emmanuel P
  • Bewick, Mike
  • Ryan, Dermot
  • Roller‐Wirnsberger, Regina E
  • Tomazic, Peter Valentin
  • Cruz, Alvaro A
  • Kuna, Piotr
  • Samolinski, Boleslaw
  • Fokkens, Wytske J
  • Reitsma, Sietze
  • Bosse, Isabelle
  • Fontaine, Jean‐François
  • Laune, Daniel
  • Haahtela, Tari
  • Toppila‐Salmi, Sanna
  • Bachert, Claus
  • Hellings, Peter W
  • Melén, Erik
  • Wickman, Magnus
  • Bindslev‐Jensen, Carsten
  • Eller, Esben
  • O'Hehir, Robyn E
  • Cingi, Cemal
  • Gemicioğlu, Bilun
  • Kalayci, Omer
  • Ivancevich, Juan Carlos
  • Bousquet, Jean

publication date

  • April 2019